Pregnenolone

What Is It?
Pregnenolone, 3-alpha-hydroxy-5-beta-pregnen-20-one, is
a precursor to over 150 steroid hormones and is produced
naturally in the body from cholesterol.

Uses For Pregnenolone
Memory Support: Animal studies have reported that
pregnenolone may help to enhance memory by
modulating N-methyl-D-aspartate (NMDA) and gamma
aminobutyrate (GABA) receptor activity in the brain.
One study suggested that pregnenolone helped promote
post-training task learning and memory.
Immune Health: One study indicated that the 7-hydroxy
metabolites from pregnenolone may help promote healthy
immune system response.
Mood Support: Pregnenolone has been reported to help
promote feelings of emotional well-being. One study
suggested that pregnenolone supported positive mood and
feelings of motivation by mediating dopamine release.

What Is The Source?
The compound diosgenin is extracted from wild yam and
undergoes a proprietary synthetic process to develop the
pregnenolone compound. The human body cannot
metabolize wild yam into pregnenolone. This process can
only take place in a laboratory.

Recommendations
•10–30 mg per day, with a meal, preferably in the morning or early afternoon.
•Pregnenolone should only be used under the direction
and supervision of a health care practitioner.
•Practitioners are advised to test pregnenolone levels
before making the decision to commence supplementation,
and to monitor levels if supplementation is initiated,
ensuring that proper levels are maintained.
• This product should not be taken by individuals with
healthy levels of pregnenolone.
•Pregnenolone is best utilized by individuals above 40
years of age, and should not be used to enhance athletic
ability or endurance.

Are There Any Precautions Or Potential Side Effects?
Precautions:
•NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18
YEARS.
•DO NOT USE IF PREGNANT OR NURSING.
•KEEP OUT OF REACH OF CHILDREN.
•Consult a physician or licensed qualified healthcare
professional before using this product if you have, or have
a family history of, prostate cancer, prostate enlargement,
heart disease, low “good” cholesterol (HDL), or if you are
using any other dietary supplement, prescription drug, or
over-the-counter drug.
•Do not exceed the recommended serving. Exceeding the
recommended serving may cause serious adverse health
effects.

Potential Side Effects:
•Possible side effects include acne, hair loss, hair growth
on the face (in women), aggressiveness, irritability, and
increased levels of estrogen.
•Discontinue use and call a physician or licensed qualified
health care professional immediately if you experience
rapid heartbeat, dizziness, blurred vision, or other similar
symptoms.

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